GF -> GF EMTreg -> GF Ecadh -| GF Migration -> Metastasis Invasion -> Migration EMT -> Migration p63_73 -| Migration AKT1 -| Migration AKT2 -> Migration ERK_pthw -> Migration miRNA -| Migration TGFb_pthw -> Invasion WNT_pthw -> Invasion EMTreg -> Invasion EMTreg -> EMT Ecadh -| EMT p53 -> Apoptosis EMTreg -| Apoptosis p63_73 -> Apoptosis AKT1 -| Apoptosis ERK_pthw -| Apoptosis miRNA -> Apoptosis TGFb_pthw -> CCA Notch_pthw -> CCA p53 -> CCA EMTreg -> CCA p63_73 -> CCA AKT1 -| CCA AKT2 -> CCA ERK_pthw -| CCA miRNA -> CCA ECMicroenv -> TGFb_pthw Notch_pthw -> TGFb_pthw WNT_pthw -| TGFb_pthw miRNA -| TGFb_pthw ECMicroenv -> Notch_pthw p53 -| Notch_pthw p63_73 -| Notch_pthw miRNA -| Notch_pthw Notch_pthw -| WNT_pthw WNT_pthw -| WNT_pthw p53 -| WNT_pthw EMTreg -| WNT_pthw p63_73 -| WNT_pthw AKT1 -| WNT_pthw miRNA -| WNT_pthw Ecadh -| WNT_pthw DNAdamage -> p53 Notch_pthw -> p53 WNT_pthw -> p53 EMTreg -| p53 p63_73 -| p53 AKT1 -| p53 AKT2 -| p53 Notch_pthw -> EMTreg WNT_pthw -> EMTreg p53 -| EMTreg EMTreg -> EMTreg miRNA -| EMTreg DNAdamage -> p63_73 Notch_pthw -| p63_73 p53 -| p63_73 EMTreg -| p63_73 AKT1 -| p63_73 AKT2 -| p63_73 GF -> AKT1 TGFb_pthw -> AKT1 Notch_pthw -> AKT1 WNT_pthw -> AKT1 p53 -| AKT1 EMTreg -> AKT1 miRNA -| AKT1 Ecadh -| AKT1 p53 -| AKT2 EMTreg -> AKT2 miRNA -| AKT2 GF -> ERK_pthw TGFb_pthw -> ERK_pthw Notch_pthw -> ERK_pthw EMTreg -> ERK_pthw AKT1 -| ERK_pthw p53 -> miRNA EMTreg -| miRNA p63_73 -> miRNA AKT1 -| miRNA AKT2 -| miRNA EMTreg -| Ecadh AKT2 -| Ecadh $AKT1: ((((((((((!GF & !TGFb_pthw) & !Notch_pthw) & WNT_pthw) & !p53) & EMTreg) & !miRNA) & !Ecadh) | ((((((!GF & !TGFb_pthw) & Notch_pthw) & WNT_pthw) & !p53) & !miRNA) & !Ecadh)) | (((((!GF & TGFb_pthw) & WNT_pthw) & !p53) & !miRNA) & !Ecadh)) | ((((GF & WNT_pthw) & !p53) & !miRNA) & !Ecadh)) $AKT2: ((!p53 & EMTreg) & !miRNA) $Apoptosis: (((((((!p53 & !EMTreg) & !p63_73) & !AKT1) & !ERK_pthw) & miRNA) | ((((!p53 & !EMTreg) & p63_73) & !AKT1) & !ERK_pthw)) | (((p53 & !EMTreg) & !AKT1) & !ERK_pthw)) $CCA: ((((((((((((((((((((((((((!TGFb_pthw & !p53) & !EMTreg) & !p63_73) & !AKT1) & !AKT2) & miRNA) | ((((((!TGFb_pthw & !p53) & !EMTreg) & !p63_73) & !AKT1) & AKT2) & !ERK_pthw)) | (((((((!TGFb_pthw & !p53) & !EMTreg) & !p63_73) & !AKT1) & AKT2) & ERK_pthw) & miRNA)) | (((((!TGFb_pthw & !p53) & !EMTreg) & p63_73) & !AKT1) & !ERK_pthw)) | ((((((!TGFb_pthw & !p53) & !EMTreg) & p63_73) & !AKT1) & ERK_pthw) & miRNA)) | (((!TGFb_pthw & !p53) & EMTreg) & !AKT1)) | ((((!TGFb_pthw & p53) & !EMTreg) & !AKT1) & !ERK_pthw)) | (((((!TGFb_pthw & p53) & !EMTreg) & !AKT1) & ERK_pthw) & miRNA)) | (((!TGFb_pthw & p53) & EMTreg) & !AKT1)) | (((((((TGFb_pthw & !Notch_pthw) & !p53) & !EMTreg) & !p63_73) & !AKT1) & !AKT2) & miRNA)) | (((((((TGFb_pthw & !Notch_pthw) & !p53) & !EMTreg) & !p63_73) & !AKT1) & AKT2) & !ERK_pthw)) | ((((((((TGFb_pthw & !Notch_pthw) & !p53) & !EMTreg) & !p63_73) & !AKT1) & AKT2) & ERK_pthw) & miRNA)) | ((((((TGFb_pthw & !Notch_pthw) & !p53) & !EMTreg) & p63_73) & !AKT1) & !ERK_pthw)) | (((((((TGFb_pthw & !Notch_pthw) & !p53) & !EMTreg) & p63_73) & !AKT1) & ERK_pthw) & miRNA)) | ((((TGFb_pthw & !Notch_pthw) & !p53) & EMTreg) & !AKT1)) | (((((TGFb_pthw & !Notch_pthw) & p53) & !EMTreg) & !AKT1) & !ERK_pthw)) | ((((((TGFb_pthw & !Notch_pthw) & p53) & !EMTreg) & !AKT1) & ERK_pthw) & miRNA)) | ((((TGFb_pthw & !Notch_pthw) & p53) & EMTreg) & !AKT1)) | ((((TGFb_pthw & Notch_pthw) & !EMTreg) & !AKT1) & !ERK_pthw)) | (((((TGFb_pthw & Notch_pthw) & !EMTreg) & !AKT1) & ERK_pthw) & miRNA)) | (((TGFb_pthw & Notch_pthw) & EMTreg) & !AKT1)) $EMT: (EMTreg & !Ecadh) $EMTreg: ((((((!Notch_pthw & !WNT_pthw) & !p53) & EMTreg) & !miRNA) | (((!Notch_pthw & WNT_pthw) & !p53) & !miRNA)) | ((Notch_pthw & !p53) & !miRNA)) $ERK_pthw: (((((((!GF & !TGFb_pthw) & !Notch_pthw) & EMTreg) & !AKT1) | (((!GF & !TGFb_pthw) & Notch_pthw) & !AKT1)) | ((!GF & TGFb_pthw) & !AKT1)) | (GF & !AKT1)) $Ecadh: (!EMTreg & !AKT2) $GF: (((!GF & EMTreg) & !Ecadh) | (GF & !Ecadh)) $Invasion: (((!TGFb_pthw & WNT_pthw) | ((TGFb_pthw & !WNT_pthw) & EMTreg)) | (TGFb_pthw & WNT_pthw)) $Metastasis: Migration $Migration: ((((((Invasion & EMT) & !p63_73) & !AKT1) & AKT2) & ERK_pthw) & !miRNA) $Notch_pthw: (((ECMicroenv & !p53) & !p63_73) & !miRNA) $TGFb_pthw: ((((!ECMicroenv & Notch_pthw) & !WNT_pthw) & !miRNA) | ((ECMicroenv & !WNT_pthw) & !miRNA)) $WNT_pthw: (((((((!Notch_pthw & !WNT_pthw) & !p53) & !EMTreg) & !p63_73) & !AKT1) & !miRNA) & !Ecadh) $miRNA: (((((!p53 & !EMTreg) & p63_73) & !AKT1) & !AKT2) | (((p53 & !EMTreg) & !AKT1) & !AKT2)) $p53: ((((((((!DNAdamage & !Notch_pthw) & WNT_pthw) & !EMTreg) & !p63_73) & !AKT1) & !AKT2) | (((((!DNAdamage & Notch_pthw) & !EMTreg) & !p63_73) & !AKT1) & !AKT2)) | ((((DNAdamage & !EMTreg) & !p63_73) & !AKT1) & !AKT2)) $p63_73: (((((DNAdamage & !Notch_pthw) & !p53) & !EMTreg) & !AKT1) & !AKT2)